Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG
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چکیده
منابع مشابه
Feasibility and advantage of adding 131I-MIBG to 90Y-DOTATOC for treatment of patients with advanced stage neuroendocrine tumors
BACKGROUND Peptide receptor radionuclide therapy (PRRT) is an effective form of treatment for patients with metastatic neuroendocrine tumors (NETs). However, delivering sufficient radiation dose to the tumor to result in a high percentage of long-term tumor remissions remains challenging because of the limits imposed on administered activity levels by radiation damage to normal tissues. The goa...
متن کاملFactors predicting tracer uptake in somatostatin receptor and MIBG scintigraphy of metastatic gastroenteropancreatic neuroendocrine tumors.
UNLABELLED Radiolabeled octreotide analogs (Oct) and metaiodobenzylguanidine (MIBG) offer 2 different approaches for imaging and targeting metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NET). Despite successful establishment of the revised World Health Organization (WHO) classification, which distinguishes between low- and high-grade malignant GEP-NET, there is a lack of scintigra...
متن کاملEnhanced tumor uptake in neuroendocrine tumors after intraarterial application of 131I-MIBG.
UNLABELLED 131I-labeled metaiodobenzylguanidine (MIBG) is an established treatment modality for neuroendocrine tumors. Because of low tumor doses, it has a predominantly palliative character. Our approach was to investigate whether intraarterial application of 131I-MIBG has the potential to enhance tumor uptake. METHODS Seventeen patients with primary or metastasized neuroendocrine tumors rec...
متن کامل131I-MIBG imaging in evaluation of neuro-endocrine (APUD) tumors [Persian]
In this study, l-131-MIBG imaging was performed in 44 patients with clinical suspicion of tumors originating from neuro-endocrine system. The patients were referred to our department following plasma and urinary measurement of epinephrine, norepinehrine and vanilmandelic acidfVMA). Radionuclide imaging was performel as a comparative or confirmatory measure in all patients who had previous...
متن کامل68Ga-DOTATATE PET/CT Compared with 131I-MIBG SPECT/CT in the Evaluation of Neural Crest Tumors
Objective(s): 68Ga-DOTATATE positron emission tomography (PET)/computed tomography (CT) has shown promising results in imaging of neural crest tumors (NCT). Herein, we compared the performance of 68Ga-DOTATATE PET/CT and 131I-MIBG single photon emission computed tomography (SPECT)/CT in the initial diagnosis, staging and follow-up of pa...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2018
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.117.202150